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Becker's Nevus with Ipsilateral Breast Hypoplasia: Improvement with Spironolactone
Jae Hoon Jung, You Chan Kim, Hyang Joon Park and Yong Woo Cinn
Department of Dermatology, College of Medicine, Dankook University Hospital, Cheonan, Korea.
Ipsilateral breast hypoplasia is a rare abnormality in Becker's nevus. The pathogenesis of the breast hypoplasia is not understood, but an increased level of androgenic receptor in the affected area may play a role. We report a case of Becker's nevus with ipsilateral breast hypoplasia. Spironolactone, an anti-androgenic agent, was tried for treatment of the hypoplasia, and, one month later, breast enlargement was seen in only the hypoplastic breast with Becker's nevus. This finding supports the theory that breast hypoplasia in Becker's nevus is related to an increase in androgenic receptor.
key words: ipsilateral breast hypoplasia; Becker's nevus; spironolactone
Received October 4, 2002; Accepted for publication December 3, 2002
Reprint requests to: You Chan Kim, M.D., Department of Dermatology, College of Medicine, Dankook University Hospital, 16-5, Anseo-dong, Cheonan, Chungcheong Nam Do, 330-714, Korea.
J Dermatol 30 (2): 154-156, 2003
Japanese Dermatological Association