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- Original article -
Basal Cell Carcinoma with Sarcomatoid Features (Sarcomatoid Carcinoma): Report of a Case and Review of the Literature
Carmen Gómez-Espejo, Alberto Herrera-Sabal, Juan José Ríos-Martín and Francisco Camacho-Martínez
Department of Dermatology, Virgen Macarena Hospital, Seville, Spain.
We report a new case of sarcomatoid carcinoma, which showed cellular features of basal cell carcinoma and malignant fibrous myxoid histiocytoma. For this new case and rare neoplasm, we propose the designation of sarcomatoid basal cell carcinoma, as both components were intimately intermingled, the spindle cells seemed to arise from epithelial cells, and both tumoral components showed the same immunohistochemistry expression, cytokeratin and P53 protein, suggesting a monoclonal origin.The epithelial component, a basal cell carcinoma, may have been the first component in the carcinogenesis process.
key words: cutaneous neoplasm; sarcomatoid carcinoma; carcinosarcoma; immunohistochemistry; P53 protein
Received July 8, 2002; Accepted for publication April 22, 2003
Reprint requests to: Prof. Francisco Camacho-Martínez, Department of Dermatology, Virgen Macarena Hospital, Avenida Dr Fedriani s/n. 41009-Seville, Spain.
J Dermatol 30 (7): 543-549, 2003
Japanese Dermatological Association
http://www.dermatol.or.jp
